Panadol Extra Advance Special Precautions

This product contains paracetamol. Taking too much paracetamol can cause serious harm to the liver. Always read and follow the label. If symptoms persist or the patient has been diagnosed with liver or kidney impairment, the patient should seek medical advice before taking this medicine. Please check with the doctor before use if: underweight or malnourished; regularly drinking alcohol (the patient may need to avoid using this product altogether or limit the amount of paracetamol that is being taken); has a severe infection as this may increase the risk of metabolic acidosis.
Signs of metabolic acidosis include: deep, rapid, difficult breathing; feeling sick (nausea), being sick (vomiting); loss of appetite.
The patient should contact a doctor immediately if he/she gets a combination of these symptoms.
Before taking this medicine, make sure to consult the doctor if taking Warfarin or similar medicines used to thin the blood. The anticoagulant effect of Warfarin and other Coumarins may be enhanced by prolonged regular daily use of Acetaminophen with increased risk of bleeding; occasional doses have no significant effect.
This medicine contains caffeine. Avoid drinking too many caffeine containing drinks (e.g. tea, coffee and caffeine-containing canned drinks) when taking this medicine. High caffeine intake can result in difficulty sleeping, shaking and an uncomfortable feeling in the chest caused by fluttering heartbeat.
This medicine contains Sodium methyl-, Sodium ethyl- and Sodium propyl-parahydroxybenzoates (E219, E215, E217) which may cause allergic reactions (signs or symptoms may possibly be delayed). The product contains 0.1736mg of sodium per tablet.
Do not take this medicine if taking any other prescription or non-prescription medicines containing paracetamol to treat pain, fever, symptoms of cold and flu, or to aid sleep. This product is not recommended if taking lithium.
Use in Children: Keep this and all medications out of reach of children.
Use in Pregnancy: This product is not recommended for use during pregnancy due to the possible increased risk of spontaneous abortion associated with caffeine consumption.
Use in Lactation: Use during breast-feeding should be avoided. Caffeine in breast milk may potentially have a stimulating effect on breast fed infants but significant toxicity has not been observed.